Type I (brain type) creatine phosphokinase (CPK) activity in rat platelets

Herbert Y. Meltzer; Andrew Guschwan

doi:10.1016/0024-3205(72)90088-4

Type I (brain type) creatine phosphokinase (CPK) activity in rat platelets

Herbert Y. Meltzer^*, Andrew Guschwan

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Studies on the difference in creating phosphokinase (CPK) activity of platelet-rich-plasma and platelet suspension before and after freezing and thawing demonstrated the presence of CPK activity in rat and rabbit platelets but not in the platelets of dogs, monkeys and humans. The CPK activity of rat and rabbit platelets was 61 ± 18 mU/10⁸ platelets and 88 ± 23 mU/10⁸ platelets respectively. The Type I (brain type) isoenzyme of CPK was found in rat platelets.

Original language	English (US)
Pages (from-to)	121-130
Number of pages	10
Journal	Life Sciences
Volume	11
Issue number	3 PART 2
DOIs	https://doi.org/10.1016/0024-3205(72)90088-4
State	Published - Feb 8 1972

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Pharmacology, Toxicology and Pharmaceutics(all)

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10.1016/0024-3205(72)90088-4

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title = "Type I (brain type) creatine phosphokinase (CPK) activity in rat platelets",

abstract = "Studies on the difference in creating phosphokinase (CPK) activity of platelet-rich-plasma and platelet suspension before and after freezing and thawing demonstrated the presence of CPK activity in rat and rabbit platelets but not in the platelets of dogs, monkeys and humans. The CPK activity of rat and rabbit platelets was 61 ± 18 mU/108 platelets and 88 ± 23 mU/108 platelets respectively. The Type I (brain type) isoenzyme of CPK was found in rat platelets.",

author = "Meltzer, {Herbert Y.} and Andrew Guschwan",

note = "Funding Information: Acknowledgement-Supported in part by State of Illinois Grant 231-12-RD, USPHS MH 16-127, and a grant from the Scottish Rite Foundation . Dr . Meltzer is the recipient of Research Career Development bard K02 MH 47808. The technical assistance of Mrs. Suzanne Mrozak is gratefully appreciated .",

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T1 - Type I (brain type) creatine phosphokinase (CPK) activity in rat platelets

AU - Meltzer, Herbert Y.

AU - Guschwan, Andrew

N1 - Funding Information: Acknowledgement-Supported in part by State of Illinois Grant 231-12-RD, USPHS MH 16-127, and a grant from the Scottish Rite Foundation . Dr . Meltzer is the recipient of Research Career Development bard K02 MH 47808. The technical assistance of Mrs. Suzanne Mrozak is gratefully appreciated .

PY - 1972/2/8

Y1 - 1972/2/8

N2 - Studies on the difference in creating phosphokinase (CPK) activity of platelet-rich-plasma and platelet suspension before and after freezing and thawing demonstrated the presence of CPK activity in rat and rabbit platelets but not in the platelets of dogs, monkeys and humans. The CPK activity of rat and rabbit platelets was 61 ± 18 mU/108 platelets and 88 ± 23 mU/108 platelets respectively. The Type I (brain type) isoenzyme of CPK was found in rat platelets.

AB - Studies on the difference in creating phosphokinase (CPK) activity of platelet-rich-plasma and platelet suspension before and after freezing and thawing demonstrated the presence of CPK activity in rat and rabbit platelets but not in the platelets of dogs, monkeys and humans. The CPK activity of rat and rabbit platelets was 61 ± 18 mU/108 platelets and 88 ± 23 mU/108 platelets respectively. The Type I (brain type) isoenzyme of CPK was found in rat platelets.

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EP - 130

JO - Life Sciences

JF - Life Sciences

IS - 3 PART 2

ER -

Type I (brain type) creatine phosphokinase (CPK) activity in rat platelets

Abstract

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