Typhlitis complicating autologous blood stem cell transplantation for breast cancer

L. Boggio, R. Pooley, S. I. Roth, J. N. Winter*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Three cases of typhlitis occurring during autologous blood stem cell transplantation (ABSCT) for metastatic breast cancer are described. Typhlitis is a rare complication of neutropenia and has uncommonly been reported in the autologous transplant setting. Although it has been most commonly described in children with leukemia, typhlitis has increasingly been reported in adult leukemias and in association with neutropenia secondary to chemotherapy for a number of solid tumors. Only five previous cases of typhlitis in the setting of ABSCT have been described. Whereas diarrhea and fever are common toxicities associated with high-dose chemotherapy, it is likely that many cases of typhlitis go unrecognized.

Original languageEnglish (US)
Pages (from-to)321-326
Number of pages6
JournalBone Marrow Transplantation
Volume25
Issue number3
DOIs
StatePublished - 2000

Keywords

  • Breast cancer
  • Neutropenic enterocolitis
  • Stem cell transplantation
  • Typhlitis

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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