TY - JOUR
T1 - Ultrasonic vocalizations as indices of affective states in rats
AU - Knutson, Brian
AU - Burgdorf, Jeffrey
AU - Panksepp, Jaak
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2002/11
Y1 - 2002/11
N2 - Adult rats spontaneously vocalize in ultrasonic frequencies. Although these ultrasonic vocalizations (USVs) have been described as by-products of locomotor activity or social signals, accumulating evidence suggests that they may also index anticipatory affective states. Converging ethological, pharmacological, and brain stimulation research indicates that whereas long low-frequency (> 0.3-s, ∼22-kHz) USVs occur during anticipation of punishment or avoidance behavior, short, high-frequency (< 0.3-s, ∼50-kHz) USVs typically occur during anticipation of reward or approach behavior. Thus, long 22-kHz USVs may index a state of negative activation, whereas short, 50-kHz USVs may instead index a state of positive activation. This hypothesis has theoretical implications for understanding the brain circuitry underlying mammalian affective states and clinical applicability for modeling hedonic properties of different psychotropic compounds.
AB - Adult rats spontaneously vocalize in ultrasonic frequencies. Although these ultrasonic vocalizations (USVs) have been described as by-products of locomotor activity or social signals, accumulating evidence suggests that they may also index anticipatory affective states. Converging ethological, pharmacological, and brain stimulation research indicates that whereas long low-frequency (> 0.3-s, ∼22-kHz) USVs occur during anticipation of punishment or avoidance behavior, short, high-frequency (< 0.3-s, ∼50-kHz) USVs typically occur during anticipation of reward or approach behavior. Thus, long 22-kHz USVs may index a state of negative activation, whereas short, 50-kHz USVs may instead index a state of positive activation. This hypothesis has theoretical implications for understanding the brain circuitry underlying mammalian affective states and clinical applicability for modeling hedonic properties of different psychotropic compounds.
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U2 - 10.1037/0033-2909.128.6.961
DO - 10.1037/0033-2909.128.6.961
M3 - Article
C2 - 12405139
AN - SCOPUS:85047675030
VL - 128
SP - 961
EP - 977
JO - Psychological Bulletin
JF - Psychological Bulletin
SN - 0033-2909
IS - 6
ER -