Ultrasound-Accelerated Thrombolysis in Patients with Intracardiac Thrombi: A Case Series

Ajay Yadlapati, Ranya Sweis, Daniel Schimmel*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We describe a case series of 3 patients presenting with intracardiac thrombi treated with standard anticoagulation therapy and intervention with ultrasound-accelerated thrombolysis therapy. Right-sided intracardiac thrombi portend significant mortality due to their susceptibility for embolization and pulmonary embolus despite the continuation of current standard of therapy of parenteral anticoagulation and surgical embolectomy if warranted. We demonstrate the safety and clinical efficacy of ultrasound-accelerated thrombolysis therapy with the EkoSonic Endovascular System infusion catheter system (EKOS Corporation) and highlight its use in resolving intracardiac thrombi and impeding the propagation of pulmonary emboli.

Original languageEnglish (US)
Pages (from-to)E30-E33
JournalJournal of Invasive Cardiology
Issue number3
StatePublished - Mar 2016


  • EKOS
  • catheter
  • intracardiac thrombi
  • thrombolytics
  • thrombus in transit
  • ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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