Ultrasound Evaluation in Patients at Risk for Hepatocellular Carcinoma

David T. Fetzer*, Shuchi K. Rodgers, James H. Seow, Adrian A. Dawkins, Gayatri Joshi, Helena Gabriel, Aya Kamaya

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


In the context of chronic liver disease (CLD), sonographic features of hepatic steatosis, cirrhosis, and portal hypertension are discussed and examples are provided. The impact of CLD and hepatocellular carcinoma (HCC) is introduced, providing the rationale for a robust HCC screening and surveillance program for at-risk patients. The American College of Radiology Liver Imaging Reporting and Data System algorithms for screening and surveillance by ultrasound and for the definitive diagnosis of HCC by contrast-enhanced ultrasound are explained, with imaging examples provided. Contrast-enhanced ultrasound technique, limitations, and pitfalls also are introduced.

Original languageEnglish (US)
Pages (from-to)563-583
Number of pages21
JournalRadiologic clinics of North America
Issue number3
StatePublished - May 2019


  • Cirrhosis
  • Contrast-enhanced ultrasound
  • HCC
  • Screening
  • Surveillance
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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