Ultrastructural study of iron deposition in the eccrine sweat glands of patients with iron overload

V. FALANGA, P. ZHENG, R. M. LAVKER*

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

An ultrastructural study of eccrine sweat glands was carried out on three patients with iron overload (two with idiopathic haemochromatosis and one with transfusional haemosiderosis). In all three patients small electron‐dense particles were seen in both eccrine sweat glands and macrophages. They appeared primarily in the clear cells of the eccrine sweat glands as membrane‐bound irregularly shaped bodies, and were shown to contain iron by energy dispersive X‐ray microanalysis. Iron aggregates in and around sweat glands were also seen on light microscopy.

Original languageEnglish (US)
Pages (from-to)51-56
Number of pages6
JournalBritish Journal of Dermatology
Volume110
Issue number1
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Dermatology

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