Ultrathin Injectable Sensors of Temperature, Thermal Conductivity, and Heat Capacity for Cardiac Ablation Monitoring

Ahyeon Koh, Sarah R. Gutbrod, Jason D. Meyers, Chaofeng Lu, Richard Chad Webb, Gunchul Shin, Yuhang Li, Seung Kyun Kang, Yonggang Huang, Igor R. Efimov*, John A. Rogers

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Knowledge of the distributions of temperature in cardiac tissue during and after ablation is important in advancing a basic understanding of this process, and for improving its efficacy in treating arrhythmias. Technologies that enable real-time temperature detection and thermal characterization in the transmural direction can help to predict the depths and sizes of lesion that form. Herein, materials and designs for an injectable device platform that supports precision sensors of temperature and thermal transport properties distributed along the length of an ultrathin and flexible needle-type polymer substrate are introduced. The resulting system can insert into the myocardial tissue, in a minimally invasive manner, to monitor both radiofrequency ablation and cryoablation, in a manner that has no measurable effects on the natural mechanical motions of the heart. The measurement results exhibit excellent agreement with thermal simulations, thereby providing improved insights into lesion transmurality.

Original languageEnglish (US)
Pages (from-to)373-381
Number of pages9
JournalAdvanced Healthcare Materials
Issue number3
StatePublished - Feb 4 2016


  • Cardiac ablation monitoring
  • Flexible thermal sensors
  • Lesion transmurality prediction
  • Thermal property detection
  • Transmural thermal detection

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Pharmaceutical Science


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