Understanding and interpreting dominant frequency analysis of AF electrograms

Jason Ng, Jeffrey J. Goldberger*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

111 Scopus citations

Abstract

Dominant frequency analysis of atrial electrograms has been used to understand the pathophysiology of atrial fibrillation (AF). Although dominant frequency is an effective tool to estimate activation rate during AF, other factors besides activation rate may alter the results. Therefore, an adequate conceptual understanding of frequency domain analysis is required to properly use this technique and interpret the results. This review, while avoiding the use of formulas and equations, aims to explain fundamental theory of how signals can be decomposed into sine waves and how these sine waves relate to the activation rate detected from the electrograms. Through a series of examples and illustrations this relationship can be easily conceptualized. This will in turn allow the strengths and limitations of dominant frequency analysis to be better understood and improve its applicability to potential clinical usages.

Original languageEnglish (US)
Pages (from-to)680-685
Number of pages6
JournalJournal of cardiovascular electrophysiology
Volume18
Issue number6
DOIs
StatePublished - Jun 2007

Keywords

  • Atrial fibrillation
  • Dominant frequency
  • Signal processing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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