Understanding the neural mechanisms involved in sensory control of voice production

Amy L. Parkinson*, Sabina G. Flagmeier, Jordan L. Manes, Charles R. Larson, Bill Rogers, Donald A. Robin

*Corresponding author for this work

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

Auditory feedback is important for the control of voice fundamental frequency (F0). In the present study we used neuroimaging to identify regions of the brain responsible for sensory control of the voice. We used a pitch-shift paradigm where subjects respond to an alteration, or shift, of voice pitch auditory feedback with a reflexive change in F0. To determine the neural substrates involved in these audio-vocal responses, subjects underwent fMRI scanning while vocalizing with or without pitch-shifted feedback. The comparison of shifted and unshifted vocalization revealed activation bilaterally in the superior temporal gyrus (STG) in response to the pitch shifted feedback. We hypothesize that the STG activity is related to error detection by auditory error cells located in the superior temporal cortex and efference copy mechanisms whereby this region is responsible for the coding of a mismatch between actual and predicted voice F0.

Original languageEnglish (US)
Pages (from-to)314-322
Number of pages9
JournalNeuroimage
Volume61
Issue number1
DOIs
StatePublished - May 15 2012

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Keywords

  • Audio-vocal integration
  • Auditory feedback
  • FMRI
  • Pitch shift
  • Vocalization

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

Cite this

Parkinson, A. L., Flagmeier, S. G., Manes, J. L., Larson, C. R., Rogers, B., & Robin, D. A. (2012). Understanding the neural mechanisms involved in sensory control of voice production. Neuroimage, 61(1), 314-322. https://doi.org/10.1016/j.neuroimage.2012.02.068