Undifferentiated embryonal sarcoma and the role of liver transplantation

Leah Plumblee*, H. Grey, Michelle Hudspeth, Satish Nadig

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Undifferentiated embryonal sarcoma of the liver (UESL) is a rare but aggressive pediatric tumor. Historically, treatment for UESL has consisted of combination therapy with surgical resection and chemotherapy. In some cases, surgical resection is not appropriate due to limiting factors such as tumor size, location, and lack of response to treatment. Orthotopic liver transplant (OLT) has been suggested as a promising alternative in these cases. We present a case of an 8 year-old boy with a large undifferentiated embryonal sarcoma of the liver who experienced disease progression after initial neoadjuvant chemotherapy. His tumor was considered unresectable after internal tumor board review due to its size and significant vascularity, ultimately making OLT the only curative option for this patient.

Original languageEnglish (US)
Article number101284
JournalJournal of Pediatric Surgery Case Reports
StatePublished - Oct 2019
Externally publishedYes


  • Orthotopic liver transplant
  • Pediatric liver transplantation
  • Pediatric liver tumors
  • Undifferentiated embryonal sarcoma of the liver

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery


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