Unilateral calcification and contrast enhancement of the basal ganglia in a child with AIDS encephalopathy

L. G. Epstein, C. Z. Berman, L. R. Sharer, M. Khademi, F. Desposito

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

For the majority of adults and children with AIDS, the disease is associated with neurologic manifestations. In children, a progressive encephalopathy has been described that often has characteristic findings on CT scans, including diffuse cerebral atrophy with secondary enlargement of the ventricular system and symmetrical bilateral calficifations of basal ganglia and white matter adjacent to the frontal horns. In addition, contrast enhancement of the basal ganglia has been noted in association with basal ganglia calcification. This report describes a child who presented with unilateral calcification and contrast enhancement of the basal ganglia, signs of a progressive encephalopathy, and evidence of infection with AIDS retrovirus HTLV-III/LAV (human T-lymphotropic virus type III/lymphadenopathy associated virus). The child did not have clinical AIDS. The presentation of HTLV-III/LAV infection in children with neurologic signs and symptoms associated with a focal finding on CT scan makes recognition of the characteristic radiographic appearance imperative for correct diagnosis.

Original languageEnglish (US)
Pages (from-to)163-165
Number of pages3
JournalAmerican Journal of Neuroradiology
Volume8
Issue number1
StatePublished - 1987

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Unilateral calcification and contrast enhancement of the basal ganglia in a child with AIDS encephalopathy'. Together they form a unique fingerprint.

Cite this