Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides

INIS

• toxicity 66%
• membranes 66%
• ions 66%
• mitochondria 66%
• leakage 66%
• mice 33%
• data 33%
• in vivo 33%
• in vitro 33%
• nmr 33%
• mass spectrometry 33%
• single crystals 33%
• x-ray diffraction 33%
• modifications 33%
• peptides 33%
• purification 33%
• strains 33%
• water 33%
• investigations 33%
• solutions 33%
• apoptosis 33%
• permeability 33%
• amino acid sequence 33%
• alanines 33%
• sediments 33%
• depolarization 33%
• great lakes 33%
• dichroism 33%
• coumarin 33%

Immunology and Microbiology

• Peptaibol 100%
• Cytotoxicity 66%
• Cells 66%
• GI50 66%
• Amino Acid Sequence 33%
• Carboxy Terminal Sequence 33%
• Mouse Model 33%
• Depolarization 33%
• Cell Death 33%
• Purification 33%
• Metabolome 33%
• Outer Membrane 33%
• Xenograft 33%
• Mitochondrion 33%
• Protein Secondary Structure 33%
• Molecular Phylogeny 33%
• Membrane Permeability 33%
• Cuniculidae 33%
• Solution and Solubility 33%
• Aptitude 33%
• Sample 33%
• Alamethicin 33%

Biochemistry, Genetics and Molecular Biology

• Cytotoxicity 66%
• C-Terminus 33%
• Copurification 33%
• Peptide Sequence 33%
• Protein Secondary Structure 33%
• Mitochondrion 33%
• Alanine 33%
• Mammalian Cell 33%
• Membrane Permeability 33%
• Depolarization 33%
• Cell Death 33%
• Mass Spectrometry 33%
• Circular Dichroism 33%
• Metabolomics 33%
• Metabolome 33%
• Single Crystal X-Ray Diffraction 33%
• Molecular Phylogeny 33%
• Outer Membrane 33%
• Coumarin 33%
• Cell-Penetrating Peptide 33%
• Alamethicin 33%
• Sample 33%
• Aptitude 33%
• Solution and Solubility 33%