Unraveling Difficult Answers: From Genotype to Phenotype in Coronary Artery Disease

Tarek Magdy, Paul W. Burridge*

*Corresponding author for this work

Research output: Contribution to journalShort survey

Abstract

Genome-wide association studies (GWASs) have robustly found a correlation between coronary artery disease (CAD) and an intergenic region at locus 9p21.3. However, the mechanistic implication of this association is unknown. Recently in Cell, Lo Sardo et al. used hiPSC genome editing to demonstrate how this locus contributes to CAD predisposition.

Original languageEnglish (US)
Pages (from-to)203-205
Number of pages3
JournalCell stem cell
Volume24
Issue number2
DOIs
StatePublished - Feb 7 2019

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ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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