Unusual Electromyographic Findings Associated With Colchicine Neuromyopathy: A Case Report

Christina Marciniak*, Ashwin Babu, Leda Ghannad, Richard Burnstine, Susan Keeshin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


An 83-year-old man with multiple medical problems, including gout, pseudogout, and renal insufficiency, presented with more than a year of proximal weakness. He had an extensive previous medical workup, including a normal creatinine kinase. His weakness persisted despite endurance and strength training. Electrodiagnostic findings were consistent with a myopathy, although without abnormal spontaneous activity and a length-dependent neuropathy. On the basis of these findings, colchicine was discontinued. The patient experienced marked symptomatic improvement within a week. Myopathies with neuropathies may be found with the use of colchicine. This case was unusual because of the absence of abnormal spontaneous activity and increased creatinine kinase, as typically reported with colchicine myopathy. Level of Evidence V

Original languageEnglish (US)
Pages (from-to)1016-1019
Number of pages4
JournalPM and R
Issue number10
StatePublished - Oct 1 2016

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Neurology
  • Clinical Neurology


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