Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

Zejuan Li, Hao Huang, Yuanyuan Li, Xi Jiang, Ping Chen, Stephen Arnovitz, Michael D. Radmacher, Kati Maharry, Abdel Elkahloun, Xinan Yang, Chunjiang He, Miao He, Zhiyu Zhang, Konstanze Dohner, Mary Beth Neilly, Colles Price, Yves A. Lussier, Yanming Zhang, Richard A. Larson, Michelle M. Le BeauMichael A. Caligiuri, Lars Bullinger, Peter J.M. Valk, Ruud Delwel, Bob Lowenberg, Paul P. Liu, Guido Marcucci, Clara D. Bloomfield, Janet D. Rowley, Jianjun Chen*

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

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Pharmacology, Toxicology and Pharmaceutical Science