Abstract
Infection with human immunodeficiency virus type 2 (HIV-2) occurs mainly in West Africa, but an increasing number of cases have been recognized in Europe, India, and the United States. In this era of global integration, clinicians must be aware of when to consider the diagnosis of HIV-2 infection and how to test for this virus. Although there is debate regarding when therapy should be initiated and which regimen should be chosen, recent trials have provided important information on treatment options for HIV-2 infection. In this review, we present information on recent clinical advances in our understanding of HIV-2 infection and highlight remaining diagnostic and therapeutic challenges.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 780-787 |
| Number of pages | 8 |
| Journal | Clinical Infectious Diseases |
| Volume | 52 |
| Issue number | 6 |
| DOIs | |
| State | Published - Mar 15 2011 |
Funding
We would like to thank Drs Kimon Zachary and Joseph Yao for their review of and comments on sections of this paper and Dr Eric Rosenberg for information regarding HIV-1 and HIV-2 diagnostic testing. We would like to acknowledge Betsy Wonderly and Rishabh Phukan for assistance in preparing this paper. R.T.G. has received grant support from Tibotec and Gilead. Financial support. R.T.G. is supported by NIH R01 AI066992-04A1 and NIH G08LM008830-01 and by grants to the AIDS Clinical Trials Group (NIH U01 AI 694722) and the Harvard University Center for AIDS Research (NIH 2P30 AI060354-06). Potential conflicts of interest. All other authors: no conflicts.
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases
