Update on plasminogen activator inhibitor-1

Douglas Vaughan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Plasminogen activator inhibitor-1 (PAI-1) is produced by the endothelium and determines the rate and extent of fibrinolysis. Recent data on PAI-1 gene polymorphism and the potential role of glucose in regulating PAI-1 expression in vascular disease are reviewed.

Original languageEnglish (US)
JournalCanadian Journal of Cardiology
Issue numberSUPPL. D
StatePublished - Dec 1 1998


  • Fibrinolysis
  • Glucose
  • Plasminogen activator inhibitor-1

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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