Urge incontinence: Estimating environmental and obstetrical risk factors using an identical twin study

Tondalaya L. Gamble, Hongyan Du, Peter K. Sand, Sylvia M. Botros, Magdalena Rurak, Roger P. Goldberg

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Introduction and hypothesis: The objective of this study was to determine risk factors for urge urinary incontinence (UUI). Methods: A multi-item survey was administered to a community sample of identical twin sisters from 2002-2008. Generalized estimating equations accounting for cotwin correlation were used to perform three different regression models on the outcome: UUI (yes vs. no). Results: Mean age, median parity, and BMI were 41.4±16.4 (18-85), 1.0, and 26.0±6.5 (13.5-55.8), respectively. Thirty-five percent of women were post-menopausal, and 27.5% had UUI. Urge urinary incontinence was reported in 40.1% of parous versus 14.1% among nulliparous women (p<.0001). The rate of UUI was 40.6% after vaginal delivery, 36.7% after cesarean delivery, and 14.1% in nulliparous women (p<.0001). Obesity, age >40, and chronic constipation were also identified as risk factors for urge urinary incontinence. Conclusion: Risk factors for UUI include parity, age, obesity, and chronic constipation. There was a 2.5-fold increased risk of UUI after one or more births, regardless of type of delivery.

Original languageEnglish (US)
Pages (from-to)939-946
Number of pages8
JournalInternational Urogynecology Journal
Volume21
Issue number8
DOIs
StatePublished - Aug 2010

Keywords

  • Obesity
  • Overactive bladder
  • Parity
  • Risk factors
  • Urge urinary incontinence

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Urology

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