Urinary Anion Gap in Hyperchloremic Metabolic Acidosis

O. M. Wrong, K. Holroyd, E. Brown, D. C. Batlle, M. Hizon, E. Cohen, C. Gutterman, R. Gupta

Research output: Contribution to journalLetterpeer-review

5 Scopus citations


To the Editor: In their article on the use of the urinary anion gap in assessing hyperchloremic metabolic acidosis, Batlle et al. (March 10 issue)1 invite criticism on several counts. They claim that the more positive urinary anion gap (sodium plus potassium minus chloride) in patients with distal renal tubular acidosis than in acidotic “normal” controls was due to a lower urinary ammonium level. However, their own Table 1 shows that this made a minor contribution to the difference. Patients with distal tubular acidosis had a mean anion gap that was 58 mmol per liter more positive than that of.

Original languageEnglish (US)
Pages (from-to)585-587
Number of pages3
JournalNew England Journal of Medicine
Issue number9
StatePublished - Sep 1 1988

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Urinary Anion Gap in Hyperchloremic Metabolic Acidosis'. Together they form a unique fingerprint.

Cite this