Usefulness of real-time three-dimensional echocardiography for evaluation of myectomy in patients with hypertrophic cardiomyopathy

Jian Xin Qin, Takahiro Shiota, Craig R. Asher, Nicholas G. Smedira, Joon Han Shin, Deborah A. Agler, Patrick J. Nash, Neil L. Greenberg, Harry M. Lever, Bruce W. Lytle, James D. Thomas

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Real-time 3-dimensional echocardiography was performed in 10 patients with obstructive hypertrophic cardiomyopathy (HC) before and after myectomy and in 6 controls. The exact location of systolic anterior motion of the mitral leaflet was shown in all patients with HC with a predominant involvement of the medial portion in 4 patients and the middle portion in 6 patients. The smallest area of the left ventricular outflow tract was significantly smaller in patients with HC than in controls (1.4 ± 0.7 vs 5.1 ± 1.2 cm 2, p <0.01), significantly increased after myectomy (4.8 ± 1.8 cm2, p <0.01) and was associated with a reduction of the pressure gradient at rest from 63 ± 41 to 15 ± 5 mm Hg (p <0.01).

Original languageEnglish (US)
Pages (from-to)964-966
Number of pages3
JournalAmerican Journal of Cardiology
Volume94
Issue number7
DOIs
StatePublished - Oct 1 2004

Funding

This study was supported in part by grant NCC9–58 from the National Aeronautics and Space Administration, Houston, Texas, and by grant USAMRMC #02360007 from the Department of Defense, Fort Detrick, Maryland.

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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