Usefulness of tissue doppler and color M-mode indexes of left ventricular diastolic function in predicting outcomes in systolic left ventricular heart failure (from the ADEPT Study)

Richard W. Troughton, David L. Prior, Christopher M. Frampton, Patrick J. Nash, Jeremy J. Pereira, Maureen Martin, Annette Fogarty, Annitta J. Morehead, Randall C. Starling, James B. Young, James D. Thomas, Michael S. Lauer, Allan L. Klein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

104 Scopus citations

Abstract

The prognostic values of tissue Doppler imaging and color M-mode diastolic indexes were studied in 225 patients who had symptomatic systolic heart failure in the ADEPT study. The primary end point of death, transplantation, or hospitalization due to heart failure occurred in 65 patients and was independently predicted by shorter deceleration time, lower ratio of pulmonary vein systolic to diastolic velocity, and increasing levels of the ratios of early transmitral velocity to early annular velocity or velocity of propagation. For the ratio of early transmitral velocity to early annular velocity, this prediction was additive to deceleration time. Newer diastolic indexes provide an independent prediction of clinical outcomes.

Original languageEnglish (US)
Pages (from-to)257-262
Number of pages6
JournalAmerican Journal of Cardiology
Volume96
Issue number2
DOIs
StatePublished - Jul 15 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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