TY - JOUR
T1 - Using item response theory to optimize measurement of chronic stress in pregnancy
AU - Borders, Ann E B
AU - Lai, Jin Shei
AU - Wolfe, Kaitlin
AU - Qadir, Sameen
AU - Peng, Jie
AU - Kim, Kwang Youn
AU - Keenan-Devlin, Lauren
AU - Holl, Jane
AU - Grobman, William
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Objective Utilize Rasch analysis to develop an optimized self-reported measure of stress in pregnancy and examine the association with patient demographics and biologic measures of stress. Study design Measured self-reported stress in pregnant women using 12 existing scales. Collected blood for biologic measures of stress (Epstein Barr Virus [EBV], C-Reactive Protein [CRP], Corticotropin Reactive Hormone [pCRH], and Adenocorticotropin Hormone [ACTH]). Used multidimensional scaling and Rasch analysis to produce an item reduced self-report measure. Results Enrolled 112 women. Survey items reduced to two factors: perceived stressors and buffers of stress. Women with a domestic partner had lower perceived stress (p = 0.003). Caucasian women reported higher buffers of stress (p = 0.045), as did women with private insurance (p < 0.001), a planned pregnancy (p < 0.01), and a domestic partner (p < 0.001). Women with higher buffers of stress had lower levels of pCRH (adjusted p = 0.01). Conclusion Item reduced, optimized measures of stress were associated with significant differences in patient demographics and biologic measures of stress.
AB - Objective Utilize Rasch analysis to develop an optimized self-reported measure of stress in pregnancy and examine the association with patient demographics and biologic measures of stress. Study design Measured self-reported stress in pregnant women using 12 existing scales. Collected blood for biologic measures of stress (Epstein Barr Virus [EBV], C-Reactive Protein [CRP], Corticotropin Reactive Hormone [pCRH], and Adenocorticotropin Hormone [ACTH]). Used multidimensional scaling and Rasch analysis to produce an item reduced self-report measure. Results Enrolled 112 women. Survey items reduced to two factors: perceived stressors and buffers of stress. Women with a domestic partner had lower perceived stress (p = 0.003). Caucasian women reported higher buffers of stress (p = 0.045), as did women with private insurance (p < 0.001), a planned pregnancy (p < 0.01), and a domestic partner (p < 0.001). Women with higher buffers of stress had lower levels of pCRH (adjusted p = 0.01). Conclusion Item reduced, optimized measures of stress were associated with significant differences in patient demographics and biologic measures of stress.
KW - Biomarkers
KW - Chronic stress
KW - Item response theory
KW - Pregnancy
KW - Self-reported stress
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U2 - 10.1016/j.ssresearch.2016.12.003
DO - 10.1016/j.ssresearch.2016.12.003
M3 - Article
C2 - 28364845
AN - SCOPUS:85009508010
SN - 0049-089X
VL - 64
SP - 214
EP - 225
JO - Social Science Research
JF - Social Science Research
ER -