This chapter reviews the use of self-assembled monolayers of alkanethiolates on gold to control the interactions of proteins and cells with man-made materials. The work is based on the ability of monolayers that present oligo(ethylene glycol) groups to resist the non-specific adsorption of protein. The chapter describes the use of functionalized monolayers for the bio- and chemo-specific adsorption of proteins. The chapter concludes with a discussion of techniques that can pattern the formation of monolayers and that can prepare tailored substrates for the control of cell attachment.
|Original language||English (US)|
|Number of pages||13|
|Journal||ACS Symposium Series|
|State||Published - 1997|
ASJC Scopus subject areas
- Chemical Engineering(all)