Endothelin-1 is a potent vasoconstrictive peptide that plays an important role in ex vivo lung perfusion. ET-1 expression levels are predictive of lung transplant outcomes and represent a valuable monitoring tool for surgeons; however, traditional techniques that measure [ET-1] are not suitable for the transplant setting. Herein, we demonstrate a new assay that rapidly measures ET-1 peptide levels in lung perfusate.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Dec 21 2015|
ASJC Scopus subject areas
- Analytical Chemistry
- Environmental Chemistry