TY - JOUR
T1 - Uterine Artery Embolization
T2 - A Treatment Option for Symptomatic Fibroids in Postmenopausal Women
AU - Chrisman, Howard B
AU - Minocha, Jeet
AU - Ryu, Robert K.
AU - Vogelzang, Robert L
AU - Nikolaidis, Paul
AU - Omary, Reed A.
PY - 2007/3/1
Y1 - 2007/3/1
N2 - The authors tested the hypothesis that UAE is an effective treatment option in postmenopausal women with fibroid-related bulk symptoms. The authors retrospectively reviewed a prospectively acquired HI-IQ database. Between 2001 and 2004, 24 women with an average age of 52 years meeting the Stages of Reproductive Aging Workshop criteria for menopause underwent UAE for fibroid-related bulk symptoms. All patients underwent preprocedural gadolinium-enhanced magnetic resonance (MR) imaging to confirm the presence of fibroid disease and exclude other pathology. These patients were followed at 1-, 3-, 6-, 12-, and 24-month intervals to assess their clinical response to therapy. Clinical success was defined as a qualitative reduction in bulk symptoms. Postprocedural gadolinium-enhanced MR imaging was performed routinely between 3 and 6 months and at 12 or 24 months, if indicated. Technical success was achieved in 24 of 24 (100%) patients. The follow-up period ranged from 1 to 24 months with an average of 9 months. Clinical success was achieved in 22 of 24 (92%) women. There were no major complications in any of the patients. Mean uterine volume was reduced by 564 cc (P < .0001). Mean dominant uterine fibroid volume was reduced by 180 cm3 (P = .0015). Uterine artery embolization is a viable treatment option in carefully selected postmenopausal women with fibroid-related bulk symptoms.
AB - The authors tested the hypothesis that UAE is an effective treatment option in postmenopausal women with fibroid-related bulk symptoms. The authors retrospectively reviewed a prospectively acquired HI-IQ database. Between 2001 and 2004, 24 women with an average age of 52 years meeting the Stages of Reproductive Aging Workshop criteria for menopause underwent UAE for fibroid-related bulk symptoms. All patients underwent preprocedural gadolinium-enhanced magnetic resonance (MR) imaging to confirm the presence of fibroid disease and exclude other pathology. These patients were followed at 1-, 3-, 6-, 12-, and 24-month intervals to assess their clinical response to therapy. Clinical success was defined as a qualitative reduction in bulk symptoms. Postprocedural gadolinium-enhanced MR imaging was performed routinely between 3 and 6 months and at 12 or 24 months, if indicated. Technical success was achieved in 24 of 24 (100%) patients. The follow-up period ranged from 1 to 24 months with an average of 9 months. Clinical success was achieved in 22 of 24 (92%) women. There were no major complications in any of the patients. Mean uterine volume was reduced by 564 cc (P < .0001). Mean dominant uterine fibroid volume was reduced by 180 cm3 (P = .0015). Uterine artery embolization is a viable treatment option in carefully selected postmenopausal women with fibroid-related bulk symptoms.
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U2 - 10.1016/j.jvir.2006.12.723
DO - 10.1016/j.jvir.2006.12.723
M3 - Article
C2 - 17377194
AN - SCOPUS:34247241579
SN - 1051-0443
VL - 18
SP - 451
EP - 454
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 3
ER -