Uterine fibroids are benign smooth muscle tumors of the uterine wall. They are the most common tumor in women and are present in up to 80% of all women by the age of 50 (1). Although most uterine fibroids are asymptomatic, when symptoms do occur, they can be severe enough to significantly impact a woman’s quality of life. Typical symptoms include heavy and irregular menstrual bleeding with accompanying anemia, dysmenorrhea (painful menses), pelvic pain, increased urinary frequency, infertility, early pregnancy loss, and dyspareunia (painful sexual intercourse), among others (2,3). Fibroids are the leading indication for hysterectomies in the United States and account for up to $34.4 billion annually in health care costs (4). In addition, because of the severity of the symptoms, fibroids may preclude women from working, which adds an impressive $17.2 billion annually to the financial burden of this condition (4).
|Original language||English (US)|
|Title of host publication||The Endometrial Factor|
|Subtitle of host publication||A Reproductive Precision Medicine Approach|
|Number of pages||10|
|State||Published - Jan 1 2017|
ASJC Scopus subject areas