Uterine fibroids and the endometrium

Deborah E. Ikhena, Serdar E. Bulun

Research output: Chapter in Book/Report/Conference proceedingChapter


Uterine fibroids are benign smooth muscle tumors of the uterine wall. They are the most common tumor in women and are present in up to 80% of all women by the age of 50 (1). Although most uterine fibroids are asymptomatic, when symptoms do occur, they can be severe enough to significantly impact a woman’s quality of life. Typical symptoms include heavy and irregular menstrual bleeding with accompanying anemia, dysmenorrhea (painful menses), pelvic pain, increased urinary frequency, infertility, early pregnancy loss, and dyspareunia (painful sexual intercourse), among others (2,3). Fibroids are the leading indication for hysterectomies in the United States and account for up to $34.4 billion annually in health care costs (4). In addition, because of the severity of the symptoms, fibroids may preclude women from working, which adds an impressive $17.2 billion annually to the financial burden of this condition (4).

Original languageEnglish (US)
Title of host publicationThe Endometrial Factor
Subtitle of host publicationA Reproductive Precision Medicine Approach
PublisherCRC Press
Number of pages10
ISBN (Electronic)9781498740401
ISBN (Print)9781498740395
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Uterine fibroids and the endometrium'. Together they form a unique fingerprint.

Cite this