Uterus transplantation in women who are genetically XY

Amani Sampson, Laura L. Kimberly, Kara Nicole Goldman, David L. Keefe, Gwendolyn P. Quinn*

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Uterus transplantation is an emerging technology adding to the arsenal of treatments for infertility; specifically the only available treatment for uterine factor infertility. Ethical investigations concerning risks to uteri donors and transplant recipients have been discussed in the literature. However, missing from the discourse is the potential of uterus transplantation in other groups of genetically XY women who experience uterine factor infertility. There have been philosophical inquiries concerning uterus transplantation in genetically XY women, which includes transgender women and women with complete androgen insufficiency syndrome. We discuss the potential medical steps necessary and associated risks for uterus transplantation in genetically XY women. Presently, the medical technology does not exist to make uterus transplantation a safe and effective option for genetically XY women, however this group should not be summarily excluded from participation in trials. Laboratory research is needed to better understand and reduce medical risk and widen the field to all women who face uterine factor infertility.

Original languageEnglish (US)
Pages (from-to)687-689
Number of pages3
JournalJournal of Medical Ethics
Volume45
Issue number10
DOIs
StatePublished - Oct 1 2019

Keywords

  • ethics
  • obstetrics and gynaecology
  • reproductive medicine
  • sexuality/gender
  • transplantation

ASJC Scopus subject areas

  • Issues, ethics and legal aspects
  • Health(social science)
  • Arts and Humanities (miscellaneous)
  • Health Policy

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