@article{18cc52fd3bc74ed9817a7c7fde3220a4,
title = "UV-responsive cyclic peptide progelator bioinks",
abstract = "We describe cyclic peptide progelators which cleave in response to UV light to generate linearized peptides which then self-assemble into gel networks. Cyclic peptide progelators were synthesized, where the peptides were sterically constrained, but upon UV irradiation, predictable cleavage products were generated. Amino acid sequences and formulation conditions were altered to tune the mechanical properties of the resulting gels. Characterization of the resulting morphologies and chemistry was achieved through liquid phase and standard TEM methods, combined with matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS).",
author = "Carlini, {Andrea S.} and Touve, {Mollie A.} and H{\'e}ctor Fern{\'a}ndez-Caro and Thompson, {Matthew P.} and Cassidy, {Mary F.} and Wei Cao and Gianneschi, {Nathan C.}",
note = "Funding Information: This research was conducted with Government support under and awarded by DoD through an AFOSR MURI (FA9550-16-1-0150) and a National Defense Science and Engineering Graduate Fellowship to M. A. T. (32 CFR 168a). A. C. would like to thank the NSF for a Graduate Research Fellowship (DGE-1144086). H. F.-C. thanks Xunta de Galicia (Predoctoral fellowship: ED481A-2017/047). The authors are also grateful for the support of an NIH Director's Transformative Research Award (R01HL117326), part of the NIH Common Fund, and the NHLBI (R01HL139001). This work made use of the EPIC facility of Northwestern University's NUANCE Center, which has received support from the So and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205); the MRSEC program (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; and the State of Illinois, through the IIN. This work also made use of the IMSERC at Northwestern University, which has received support from the So and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205); the State of Illinois and International Institute for Nanotechnology (IIN). Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2019",
doi = "10.1039/c9fd00026g",
language = "English (US)",
volume = "219",
pages = "44--57",
journal = "Faraday Discussions",
issn = "1359-6640",
publisher = "Royal Society of Chemistry",
}