Valproic acid for the treatment of hemorrhagic shock: A dose-optimization study

Keyphrases

• Dose Optimization 100%
• Optimization Study 100%
• Valproic Acid 100%
• Hemorrhagic Shock 100%
• Split Dose 33%
• Dose Escalation 25%
• High Dose 16%
• Survival Pathways 16%
• Histone Acetylation 16%
• PI3K Pathway 8%
• Shock 8%
• Western Blot Analysis 8%
• Survival Benefit 8%
• AKT1 8%
• Acetylation 8%
• Histone H3 8%
• Protein Signaling 8%
• Similarity Model 8%
• Dose Effect 8%
• Acetylated Histone 8%
• Pro-survival 8%
• Glycogen Synthase Kinase 3 (GSK3) 8%
• Sublethal 8%
• Dose Administration 8%
• Relative Percent Survival 8%

Biochemistry, Genetics and Molecular Biology

• Histone Acetylation 100%
• Acetylation 50%
• Signaling Protein 50%
• Animal Models 50%
• Drug Megadose 50%
• GSK-3 50%
• Histone H3 50%
• Histone 50%
• Western Blotting 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Sodium Valproate 100%
• Hemorrhagic Shock 100%
• Histone 25%
• Bleeding 16%
• Western Blot 8%
• Cytoprotective Agent 8%
• Glycogen Synthase Kinase 8%
• Histone H3 8%