Values clarification and parental decision making about newborn genomic sequencing

Susana Peinado*, Ryan S. Paquin, Christine Rini, Myra Roche, Rita M. Butterfield, Jonathan S. Berg, Cynthia M. Powell, Donald B. Bailey, Megan A. Lewis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Using an online decision aid developed to support parental decision making about newborn genomic sequencing, we tested whether adding a values clarification exercise to educational content would improve decision making outcomes and influence intention to pursue genomic sequencing. We also examined whether the effect of values clarification varied depending on one's health literacy level. Method: In an online experiment, women and men aged 18 to 44 who were either pregnant or had a pregnant partner, were currently trying to get pregnant, or were preparing for a pregnancy within the next 2 years were randomly assigned to complete either a decision aid with educational information about newborn genomic sequencing or a decision aid with the same educational information and a values clarification exercise. Results: Of the 1,000 participants who completed the decision aid, those who completed the values clarification exercise reported less decision regret, F(1, 995) = 6.19, p =.01, and were clearer about their personal values, F(1, 995) = 6.39, p =.01. Moderation analyses revealed that the benefit of values clarification on decisional conflict was particularly evident among participants with lower health literacy, B = x3.94, SE = 1.67, t = x2.36, p =.018. There was not a significant moderation effect of health literacy and decision aid condition on decision regret. Conclusions: Adding a values clarification exercise to decision aids for parents making decisions about genomic sequencing may improve the decision-making experience and provide some benefit to individuals with lower health literacy.

Original languageEnglish (US)
Pages (from-to)335-344
Number of pages10
JournalHealth Psychology
Volume39
Issue number4
DOIs
StatePublished - Apr 2020

Keywords

  • Genomic sequencing
  • Health literacy
  • Newborn screening
  • Parental decision making
  • Values clarification

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health

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