TY - JOUR
T1 - Vancomycin-resistant enterococci
T2 - Clinical, microbiologic, and epidemiologic features
AU - Noskin, Gary A.
PY - 1997/7
Y1 - 1997/7
N2 - Enterococci have emerged as important nosocomial pathogens with increasing antimicrobial resistance. Within the past 5 years, vancomycin-resistant strains have disseminated throughout the United States and Europe. Many of these organisms are also highly resistant to β-lactams and aminoglycosides, making them virtually untreatable. Because optimal therapy for these infections is unknown, attributable mortality rates for patients with vancomycin-resistant enterococcal bacteremia are extremely high. Recently identified risk factors for acquisition include prolonged hospitalization, prior antibiotic use, and serious underlying illness. Until effective therapy is available, prevention of infection by proper infection control procedures and judicious antibiotic use is critical.
AB - Enterococci have emerged as important nosocomial pathogens with increasing antimicrobial resistance. Within the past 5 years, vancomycin-resistant strains have disseminated throughout the United States and Europe. Many of these organisms are also highly resistant to β-lactams and aminoglycosides, making them virtually untreatable. Because optimal therapy for these infections is unknown, attributable mortality rates for patients with vancomycin-resistant enterococcal bacteremia are extremely high. Recently identified risk factors for acquisition include prolonged hospitalization, prior antibiotic use, and serious underlying illness. Until effective therapy is available, prevention of infection by proper infection control procedures and judicious antibiotic use is critical.
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U2 - 10.1016/S0022-2143(97)90054-8
DO - 10.1016/S0022-2143(97)90054-8
M3 - Review article
C2 - 9242362
AN - SCOPUS:0031193463
VL - 130
SP - 14
EP - 20
JO - Translational Research
JF - Translational Research
SN - 1931-5244
IS - 1
ER -