Vancomycin-resistant enterococci: Clinical, microbiologic, and epidemiologic features

Gary A. Noskin*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

46 Scopus citations

Abstract

Enterococci have emerged as important nosocomial pathogens with increasing antimicrobial resistance. Within the past 5 years, vancomycin-resistant strains have disseminated throughout the United States and Europe. Many of these organisms are also highly resistant to β-lactams and aminoglycosides, making them virtually untreatable. Because optimal therapy for these infections is unknown, attributable mortality rates for patients with vancomycin-resistant enterococcal bacteremia are extremely high. Recently identified risk factors for acquisition include prolonged hospitalization, prior antibiotic use, and serious underlying illness. Until effective therapy is available, prevention of infection by proper infection control procedures and judicious antibiotic use is critical.

Original languageEnglish (US)
Pages (from-to)14-20
Number of pages7
JournalJournal of Laboratory and Clinical Medicine
Volume130
Issue number1
DOIs
StatePublished - Jul 1997

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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