Abstract
The t(9;11)(p22;q23) is a recurring abnormality in acute nonlymphocytic leukemia. The analysis of complex 9;11 translocations will aid in the identification of the conserved chromosomal junction or the critical genetic alteration created by the rearrangement; however, variant translocations involving chromosomes #9 and #11 have not been reported. We have identified such variants in two patients who had acute myelomonocytic leukemia and acute monocytic leukemia, characterized by a t(9;11;18)(p22;q23;q12) and a t(9;11;13)(p22;q23;q34), respectively. The conserved junction resulting from these rearrangements is created by the translocation of chromosomal material from 9p to 11q.
Original language | English (US) |
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Pages (from-to) | 171-175 |
Number of pages | 5 |
Journal | Cancer Genetics and Cytogenetics |
Volume | 30 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1988 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research