TY - JOUR
T1 - Variation in the Color Doppler Area of a Regurgitant Jet with Changes in the Absolute Chamber Pressure
T2 - An In Vitro Study
AU - Aragam, J. R.
AU - Flachskampf, F. A.
AU - Weyman, A. E.
AU - Thomas, J. D.
N1 - Funding Information:
From the Noninvasive Cardiac Laboratory, Massachusetts General Hospital, Harvard Medical School. Presented in patt at the 39th Annual Scientific Session of the American College of Cardiology, March 1990, New Orleans, Louisiana. 'James D. Thomas, MD, is supported in part by the Bayer Fund for Cardiovascular Research, New York, N.Y. Reprint requests: James D. Thomas, MD, FACC, Department of Cardiology, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195. 27/l/37988
PY - 1992
Y1 - 1992
N2 - The color Doppler appearance of a regurgitant jet depends on jet momentum, determined in part by the pressure difference between the two chambers. However, it is not clear if absolute chamber pressure has an independent effect on jet area. To test this question, an in vitro experiment was performed in which dynamically decaying jets were created with identical initial pressure gradients but five different levels of absolute chamber pressures. At every level of chamber pressure, color Doppler images were recorded with two different transducers (3.5 and 5.0 MHz) and jet areas were measured at four different flow rates (0 to 9.9 cm3/sec). A multilinear regression model was created with jet area as the dependent variable and jet flow rate, transducer frequency, and absolute chamber pressure as independent parameters. Jet area was most strongly predicted by flow rate (univariate r = 0.90) and transducer frequency (r = 9.32). Even after adjusting for these effects, however, a small but significant (p < 0.0001) effect of absolute chamber pressure on jet area was seen with jet area rising by 0.89 cm2 for each 10 mm Hg increase in absolute chamber pressure (multivariate r = 0.96, p < 0.0001). We conclude that the color Doppler area of a regurgitant jet is dependent not only on the relative pressure and flow between the two chambers but also on the absolute chamber pressure.
AB - The color Doppler appearance of a regurgitant jet depends on jet momentum, determined in part by the pressure difference between the two chambers. However, it is not clear if absolute chamber pressure has an independent effect on jet area. To test this question, an in vitro experiment was performed in which dynamically decaying jets were created with identical initial pressure gradients but five different levels of absolute chamber pressures. At every level of chamber pressure, color Doppler images were recorded with two different transducers (3.5 and 5.0 MHz) and jet areas were measured at four different flow rates (0 to 9.9 cm3/sec). A multilinear regression model was created with jet area as the dependent variable and jet flow rate, transducer frequency, and absolute chamber pressure as independent parameters. Jet area was most strongly predicted by flow rate (univariate r = 0.90) and transducer frequency (r = 9.32). Even after adjusting for these effects, however, a small but significant (p < 0.0001) effect of absolute chamber pressure on jet area was seen with jet area rising by 0.89 cm2 for each 10 mm Hg increase in absolute chamber pressure (multivariate r = 0.96, p < 0.0001). We conclude that the color Doppler area of a regurgitant jet is dependent not only on the relative pressure and flow between the two chambers but also on the absolute chamber pressure.
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U2 - 10.1016/S0894-7317(14)80275-7
DO - 10.1016/S0894-7317(14)80275-7
M3 - Article
C2 - 1510857
AN - SCOPUS:0026886759
SN - 0894-7317
VL - 5
SP - 421
EP - 426
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 4
ER -