Vascular Cognitive Impairment

Philip B. Gorelick*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


In this chapter, we discuss a brief history of vascular cognitive impairment (VCI) and vascular dementia (VaD), the definition of the terms VCI, VaD, and other related classification terms, the epidemiology and vascular risks associated with cognitive impairment, clinical manifestations, diagnostic tests, and prospects for prevention and treatment. Stroke and cardiovascular risks have been major targets for the prevention of cognitive impairment and for the reduction of cognitive decline because these factors are modifiable, easy to measure, and can be monitored (Gorelick, Journal of Neurochemistry 144:609, 2017; Gorelick et al., Stroke 48:e284-e303, 2017). Over time, there has been acceptance of stroke and cardiovascular risks as factors predisposing to certain types of dementia including Alzheimer’s disease (AD) and other cognitively impairing disorders. And, as discussed in this chapter, major guidance statements relating to the prevention of cognitive impairment are now suggesting that stroke and cardiovascular risks be managed in an attempt to prevent cognitive impairment or possibly to slow the progression of cognitive decline (Gorelick et al., Stroke 48:e284-e303, 2017).

Original languageEnglish (US)
Title of host publicationNeurovascular Neuropsychology
Subtitle of host publicationSecond Edition
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783030495862
ISBN (Print)9783030495855
StatePublished - Jan 1 2020


  • Post-stroke dementia
  • Small vessel disease
  • Vascular cognitive impairment (VCI)
  • Vascular dementia

ASJC Scopus subject areas

  • General Psychology
  • General Medicine


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