Vasospasm and stroke attributable to ephedra-free xenadrine: Case report

Roben O. Holmes, Jinny Tavee

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Following the 2004 ban of ephedra, which was linked to several cases of stroke and myocardial infarction, manufacturers have marketed "ephedra-free" weight loss products that include the active ingredient synephrine. Despite the lack of data on safety and efficacy, synephrine is touted by its promoters as a "safe" alternative to ephedra and is often combined with caffeine, as in the supplement Xenadrine-EFX. We report a case of left middle cerebral artery vasopasm and stroke in a young healthy patient in the setting of Xenadrine-EFX use.

Original languageEnglish (US)
Pages (from-to)708-710
Number of pages3
JournalMilitary medicine
Issue number7
StatePublished - Jul 2008

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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