Abstract
Cardiopulmonary support is frequently required during lung transplantation. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been recently shown to be an acceptable and, perhaps, safer alternative to cardiopulmonary bypass machine (CBM) for lung transplantation. However, therapeutic anticoagulation used during both these techniques can cause significant bleeding diathesis, especially in the setting of re-transplantation or when severe adhesions are encountered. Technological advances have reduced the thrombogenic potential of VA-ECMO circuits and unlike CBM, VA-ECMO does not include a reservoir containing a stagnant column of blood. Here, we demonstrate that VA-ECMO can be used without therapeutic anticoagulation for short-term intraoperative support.
| Original language | English (US) |
|---|---|
| Pages (from-to) | E629-E631 |
| Journal | Journal of Thoracic Disease |
| Volume | 9 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1 2017 |
Funding
We thank Ms. Elena Susan for administrative assistance in the submission of this manuscript. This work was supported by National Institutes of Health [HL125940 to A Bharat]; and matching funds by the Thoracic Surgery Foundation [Agreement 2/3/16].
Keywords
- Anticoagulation
- Extracorporeal membrane oxygenation (ECMO)
- Heparin
- Lung transplantation
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
