Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis

Kourosh Rezania; Ori Gottlieb; Amy Guralnick; Vivek Prachand; Bobbie J. Sweitzer; Wickii Vigneswaran; Steven R. White; Raymond P. Roos

doi:10.1002/mus.24420

Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis

Kourosh Rezania^*, Ori Gottlieb, Amy Guralnick, Vivek Prachand, Bobbie J. Sweitzer, Wickii Vigneswaran, Steven R. White, Raymond P. Roos

^*Corresponding author for this work

Anesthesiology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Introduction: Patients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility. Methods: We implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines. Results: We report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE. Conclusions: These patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.

Original language	English (US)
Pages (from-to)	863-865
Number of pages	3
Journal	Muscle and Nerve
Volume	50
Issue number	5
DOIs	https://doi.org/10.1002/mus.24420
State	Published - Nov 1 2014

Keywords

ALS
DPS
DVT
Pulmonary embolism
VTE

ASJC Scopus subject areas

Physiology
Clinical Neurology
Cellular and Molecular Neuroscience
Physiology (medical)

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10.1002/mus.24420

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title = "Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis",

abstract = "Introduction: Patients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility. Methods: We implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines. Results: We report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE. Conclusions: These patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.",

keywords = "ALS, DPS, DVT, Pulmonary embolism, VTE",

author = "Kourosh Rezania and Ori Gottlieb and Amy Guralnick and Vivek Prachand and Sweitzer, {Bobbie J.} and Wickii Vigneswaran and White, {Steven R.} and Roos, {Raymond P.}",

year = "2014",

month = nov,

day = "1",

doi = "10.1002/mus.24420",

language = "English (US)",

volume = "50",

pages = "863--865",

journal = "Muscle and Nerve",

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TY - JOUR

T1 - Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis

AU - Rezania, Kourosh

AU - Gottlieb, Ori

AU - Guralnick, Amy

AU - Prachand, Vivek

AU - Sweitzer, Bobbie J.

AU - Vigneswaran, Wickii

AU - White, Steven R.

AU - Roos, Raymond P.

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Introduction: Patients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility. Methods: We implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines. Results: We report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE. Conclusions: These patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.

AB - Introduction: Patients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility. Methods: We implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines. Results: We report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE. Conclusions: These patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.

KW - ALS

KW - DPS

KW - DVT

KW - Pulmonary embolism

KW - VTE

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JO - Muscle and Nerve

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IS - 5

ER -

Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis

Abstract

Keywords

ASJC Scopus subject areas

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