Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis

Kourosh Rezania*, Ori Gottlieb, Amy Guralnick, Vivek Prachand, Bobbie J. Sweitzer, Wickii Vigneswaran, Steven R. White, Raymond P. Roos

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Introduction: Patients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility. Methods: We implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines. Results: We report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE. Conclusions: These patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.

Original languageEnglish (US)
Pages (from-to)863-865
Number of pages3
JournalMuscle and Nerve
Issue number5
StatePublished - Nov 1 2014


  • ALS
  • DPS
  • DVT
  • Pulmonary embolism
  • VTE

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


Dive into the research topics of 'Venous thromboembolism after Diaphragm Pacing in amyotrophic lateral sclerosis'. Together they form a unique fingerprint.

Cite this