Ventricular Ectopy and Arrhythmia Characteristics for Persons Living with HIV and Uninfected Controls

Alexander Meyer, Sanjay Dandamudi, Chad Achenbach, Donald Lloyd-Jones, Matthew Feinstein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Persons with HIV have elevated risk for cardiovascular disease, but little is known about the risk of ventricular ectopy and ventricular tachycardia (VE/VT) for HIV-infected (HIV+) persons. Methods: We evaluated the presence and anatomic origin of VE/VT for HIV+ persons and controls by screening a cohort using International Classification of Diseases codes and adjudicating positive screens by chart review. We sought to evaluate (1) presence of VE/VT and (2) likely anatomic origin of the VE/VT based on electrocardiogram. Results: There was no significant difference in the prevalence of VE/VT for HIV+ or uninfected persons. Among HIV+ persons, worse HIV control was associated with significantly greater odds of VE/VT. Exploratory analyses suggested that HIV+ persons may have a greater likelihood of VE/VT originating from the left ventricle. Conclusion: Although worse HIV control was associated with higher odds of VE/VT among persons with HIV, odds of VE/VT were not higher for persons with HIV than uninfected persons.

Original languageEnglish (US)
JournalJournal of the International Association of Providers of AIDS Care
Volume18
DOIs
StatePublished - May 24 2019

Keywords

  • AIDS
  • HIV
  • sudden cardiac death
  • ventricular arrhythmia
  • ventricular ectopy

ASJC Scopus subject areas

  • Immunology
  • Dermatology
  • Infectious Diseases

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