Vertebrate homeodomain proteins: families of region-specific transcription factors

C. V E Wright; K. W Y Cho; G. Oliver; E. M. De Robertis

doi:10.1016/0968-0004(89)90043-1

Vertebrate homeodomain proteins: families of region-specific transcription factors

C. V E Wright, K. W Y Cho, G. Oliver, E. M. De Robertis

Medicine, Nephrology Division

Research output: Contribution to journal › Review article › peer-review

122 Scopus citations

Abstract

Vertebrate homeodomain proteins are transcription factors whose genes can be isolated via a conserved DNA-binding domain called the homeobox. We review recent studies suggesting that one function of these genes is the early subdivision of the embryo along the antero-posterior axis into 'fields' of cells with different developmental potential.

Original language	English (US)
Pages (from-to)	52-56
Number of pages	5
Journal	Trends in Biochemical Sciences
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/0968-0004(89)90043-1
State	Published - Feb 1989

ASJC Scopus subject areas

Molecular Biology
Biochemistry

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10.1016/0968-0004(89)90043-1

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title = "Vertebrate homeodomain proteins: families of region-specific transcription factors",

abstract = "Vertebrate homeodomain proteins are transcription factors whose genes can be isolated via a conserved DNA-binding domain called the homeobox. We review recent studies suggesting that one function of these genes is the early subdivision of the embryo along the antero-posterior axis into 'fields' of cells with different developmental potential.",

author = "Wright, {C. V E} and Cho, {K. W Y} and G. Oliver and {De Robertis}, {E. M.}",

note = "Funding Information: colleagues for the unpublished whole-mount staining procedure, and Clyde Lulham (BioRad Microsciences Division) for image collection and analysis. Work in our laboratory is supported by a grant from the NIH.",

year = "1989",

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T1 - Vertebrate homeodomain proteins

T2 - families of region-specific transcription factors

AU - Wright, C. V E

AU - Cho, K. W Y

AU - Oliver, G.

AU - De Robertis, E. M.

N1 - Funding Information: colleagues for the unpublished whole-mount staining procedure, and Clyde Lulham (BioRad Microsciences Division) for image collection and analysis. Work in our laboratory is supported by a grant from the NIH.

PY - 1989/2

Y1 - 1989/2

N2 - Vertebrate homeodomain proteins are transcription factors whose genes can be isolated via a conserved DNA-binding domain called the homeobox. We review recent studies suggesting that one function of these genes is the early subdivision of the embryo along the antero-posterior axis into 'fields' of cells with different developmental potential.

AB - Vertebrate homeodomain proteins are transcription factors whose genes can be isolated via a conserved DNA-binding domain called the homeobox. We review recent studies suggesting that one function of these genes is the early subdivision of the embryo along the antero-posterior axis into 'fields' of cells with different developmental potential.

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Vertebrate homeodomain proteins: families of region-specific transcription factors

Abstract

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