Vertebrate–arthropod communication dictates tick development and pathogen transmission

Osamudiamen Ebohon, Brittany A. Hart, Brandon L. Jutras*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

Abstract

Cross-species communication drives the coordination of diverse biological processes in complex systems. Rana et al. discovered that Ixodes scapularis, the tick vector of Lyme disease, produces a receptor that binds host interferon-gamma (IFNγ) in the blood meal, which orchestrates tick development, immunity, and vector competence.

Original languageEnglish (US)
Pages (from-to)325-327
Number of pages3
JournalTrends in Parasitology
Volume39
Issue number5
DOIs
StatePublished - May 2023

Funding

Support for our studies on spirochete peptidoglycan is provided by the NIH (R01AI141958-01, R21AI159800-01), USDA (VA-160113), and the following private foundations: The Steven & Alexandra Cohen Foundation; The Bay Area Lyme Foundation; Global Lyme Alliance. The authors declare no competing interests.

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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