Vestibulodynia: A multifactorial syndrome: A case report

Julia Geynisman-Tan, William J. Ledger*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Vulvodynia is a difficult-to-treat, chronic, multifactorial malady that drastically lowers the quality of life of afflicted patients. CASE: A 68-year-old woman, who had been treated successfully for vulvodynia years before with medication, returned with a recurrence of vulvodynia symptoms that this time did not respond to treatment. She now had biopsy-confirmed lichen sclerosis and was found to have markedly elevated serum testosterone levels. An imaging study detected an ovarian lesion that, on removal, proved to be a fibrothecoma. Postoperatively the testosterone rapidly dropped to normal levels. What was unexpected and unusual was that the vulvar pain disappeared and the lichen sclerosis markedly regressed. CONCLUSION: This case demonstrates a hormonal trigger for the development of vulvodynia.

Original languageEnglish (US)
Pages (from-to)287-289
Number of pages3
JournalJournal of Reproductive Medicine
Issue number3
StatePublished - 2016


  • Fibrothecoma
  • Lichen sclerosis
  • Lichen sclerosus
  • Lichen sclerosus et atrophicus
  • Testosterone
  • Thecoma
  • Vestibulitis
  • Vestibulodynia
  • Vulvar vestibulitis
  • Vulvitis
  • Vulvodynia

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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