Infectious agents are one of the potential etiologies for the pathologic findings of the gastrointestinal (GI) specimens. Various clinical settings such as general debilitation, infancy or advanced age, immunocompromised state, hematologic malignancies, chemotherapy or diabetes predispose patients to viral infections of the GI tract. Endoscopic evaluation with biopsies are often performed as part of the diagnostic workup of such patients. Considering the site and the pattern of injury along with microscopic recognition of the viral inclusions are essential in identifying the possible cause of injury. The aim of this article is to review the most commonly encountered viral infections of the GI tract in order to provide some guidance in differentiating between the various responsible viral agents and to highlight some of the challenges faced by pathologists in approaching such cases in daily practice.
- gastrointestinal tract
- viral infections
ASJC Scopus subject areas
- Pathology and Forensic Medicine