Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network

Lewis J. Frey; Katherine A. Sward; Christopher J L Newth; Robinder G. Khemani; Martin E. Cryer; Julie L. Thelen; Rene Enriquez; Su Shaoyu; Murray M. Pollack; Rick E. Harrison; Kathleen L. Meert; Robert A. Berg; David L. Wessel; Thomas P. Shanley; Heidi Dalton; Joseph Carcillo; Tammara L. Jenkins; J. Michael Dean

doi:10.1093/jamia/ocv009

Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network

Lewis J. Frey^*, Katherine A. Sward, Christopher J L Newth, Robinder G. Khemani, Martin E. Cryer, Julie L. Thelen, Rene Enriquez, Su Shaoyu, Murray M. Pollack, Rick E. Harrison, Kathleen L. Meert, Robert A. Berg, David L. Wessel, Thomas P. Shanley, Heidi Dalton, Joseph Carcillo, Tammara L. Jenkins, J. Michael Dean

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Objectives To examine the feasibility of deploying a virtual web service for sharing data within a research network, and to evaluate the impact on data consistency and quality. Material and Methods Virtual machines (VMs) encapsulated an open-source, semantically and syntactically interoperable secure web service infrastructure along with a shadow database. The VMs were deployed to 8 Collaborative Pediatric Critical Care Research Network Clinical Centers. Results Virtual web services could be deployed in hours. The interoperability of the web services reduced format misalignment from 56% to 1% and demonstrated that 99% of the data consistently transferred using the data dictionary and 1% needed human curation. Conclusions Use of virtualized open-source secure web service technology could enable direct electronic abstraction of data from hospital databases for research purposes.

Original language	English (US)
Pages (from-to)	1271-1276
Number of pages	6
Journal	Journal of the American Medical Informatics Association
Volume	22
Issue number	6
DOIs	https://doi.org/10.1093/jamia/ocv009
State	Published - Nov 1 2015

Funding

This work was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Department of Health and Human Services, through cooperative agreements (U10HD050096, U10HD049981, U10HD063108, U10HD063106, U10HD063114, U10HD049983, U10HD050012, and U01HD049934).

Keywords

Data governance
Electronic health record
Grid
Learning health care system
Pediatric critical care
Pediatric network
Secure web services
Virtual machines
Virtualization

ASJC Scopus subject areas

Health Informatics

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10.1093/jamia/ocv009

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Frey, L. J., Sward, K. A., Newth, C. J. L., Khemani, R. G., Cryer, M. E., Thelen, J. L., Enriquez, R., Shaoyu, S., Pollack, M. M., Harrison, R. E., Meert, K. L., Berg, R. A., Wessel, D. L., Shanley, T. P., Dalton, H., Carcillo, J., Jenkins, T. L., & Michael Dean, J. (2015). Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network. Journal of the American Medical Informatics Association, 22(6), 1271-1276. https://doi.org/10.1093/jamia/ocv009

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abstract = "Objectives To examine the feasibility of deploying a virtual web service for sharing data within a research network, and to evaluate the impact on data consistency and quality. Material and Methods Virtual machines (VMs) encapsulated an open-source, semantically and syntactically interoperable secure web service infrastructure along with a shadow database. The VMs were deployed to 8 Collaborative Pediatric Critical Care Research Network Clinical Centers. Results Virtual web services could be deployed in hours. The interoperability of the web services reduced format misalignment from 56% to 1% and demonstrated that 99% of the data consistently transferred using the data dictionary and 1% needed human curation. Conclusions Use of virtualized open-source secure web service technology could enable direct electronic abstraction of data from hospital databases for research purposes.",

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author = "Frey, {Lewis J.} and Sward, {Katherine A.} and Newth, {Christopher J L} and Khemani, {Robinder G.} and Cryer, {Martin E.} and Thelen, {Julie L.} and Rene Enriquez and Su Shaoyu and Pollack, {Murray M.} and Harrison, {Rick E.} and Meert, {Kathleen L.} and Berg, {Robert A.} and Wessel, {David L.} and Shanley, {Thomas P.} and Heidi Dalton and Joseph Carcillo and Jenkins, {Tammara L.} and {Michael Dean}, J.",

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doi = "10.1093/jamia/ocv009",

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Frey, LJ, Sward, KA, Newth, CJL, Khemani, RG, Cryer, ME, Thelen, JL, Enriquez, R, Shaoyu, S, Pollack, MM, Harrison, RE, Meert, KL, Berg, RA, Wessel, DL, Shanley, TP, Dalton, H, Carcillo, J, Jenkins, TL & Michael Dean, J 2015, 'Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network', Journal of the American Medical Informatics Association, vol. 22, no. 6, pp. 1271-1276. https://doi.org/10.1093/jamia/ocv009

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AU - Sward, Katherine A.

AU - Newth, Christopher J L

AU - Khemani, Robinder G.

AU - Cryer, Martin E.

AU - Thelen, Julie L.

AU - Enriquez, Rene

AU - Shaoyu, Su

AU - Pollack, Murray M.

AU - Harrison, Rick E.

AU - Meert, Kathleen L.

AU - Berg, Robert A.

AU - Wessel, David L.

AU - Shanley, Thomas P.

AU - Dalton, Heidi

AU - Carcillo, Joseph

AU - Jenkins, Tammara L.

AU - Michael Dean, J.

N1 - Publisher Copyright: © The Author 2015.

PY - 2015/11/1

Y1 - 2015/11/1

N2 - Objectives To examine the feasibility of deploying a virtual web service for sharing data within a research network, and to evaluate the impact on data consistency and quality. Material and Methods Virtual machines (VMs) encapsulated an open-source, semantically and syntactically interoperable secure web service infrastructure along with a shadow database. The VMs were deployed to 8 Collaborative Pediatric Critical Care Research Network Clinical Centers. Results Virtual web services could be deployed in hours. The interoperability of the web services reduced format misalignment from 56% to 1% and demonstrated that 99% of the data consistently transferred using the data dictionary and 1% needed human curation. Conclusions Use of virtualized open-source secure web service technology could enable direct electronic abstraction of data from hospital databases for research purposes.

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Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network

Abstract

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Keywords

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