TY - JOUR
T1 - Visible-light optical coherence tomography
T2 - A review
AU - Shu, Xiao
AU - Beckmann, Lisa
AU - Zhang, Hao F.
N1 - Funding Information:
We acknowledge the generous financial support from the National Institutes of Health (NIH) under Grant Nos. DP3DK108248, R24EY022883, R01EY026078, R43EY026466, and R21EY027502.
Publisher Copyright:
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE).
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Visible-light optical coherence tomography (vis-OCT) is an emerging imaging modality, providing new capabilities in both anatomical and functional imaging of biological tissue. It relies on visible light illumination, whereas most commercial and investigational OCTs use near-infrared light. As a result, vis-OCT requires different considerations in engineering design and implementation but brings unique potential benefits to both fundamental research and clinical care of several diseases. Here, we intend to provide a summary of the development of vis-OCT and its demonstrated applications. We also provide perspectives on future technology improvement and applications.
AB - Visible-light optical coherence tomography (vis-OCT) is an emerging imaging modality, providing new capabilities in both anatomical and functional imaging of biological tissue. It relies on visible light illumination, whereas most commercial and investigational OCTs use near-infrared light. As a result, vis-OCT requires different considerations in engineering design and implementation but brings unique potential benefits to both fundamental research and clinical care of several diseases. Here, we intend to provide a summary of the development of vis-OCT and its demonstrated applications. We also provide perspectives on future technology improvement and applications.
KW - Brain imaging
KW - Hemodynamics
KW - Metabolic rate of oxygen
KW - Optical coherence tomography
KW - Retinal imaging
KW - Spectroscopic analysis
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U2 - 10.1117/1.JBO.22.12.121707
DO - 10.1117/1.JBO.22.12.121707
M3 - Review article
C2 - 29218923
AN - SCOPUS:85038433477
SN - 1083-3668
VL - 22
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 12
M1 - 121707
ER -