Visual classification of complicated plaques based on multidimensional image fusion

A. Hennemuth*, A. Harloff, T. Spehl, N. Pavlov, O. Friman, D. Paul, D. V. Elverfeldt, C. Kuehnel, S. Wirtz, H. Goebel, J. Mannheim, H. K. Hahn, B. Pichler, J. Hennig, M. Markl

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Multi-contrast MRI has shown to be suitable for plaque analysis, which is important for the risk assessment of internal carotid artery stenoses. The purpose of this work was the development of software prototypes, which support the development of methods for the classification and exploration of plaque-morphology in 3D and allow for a comparison with histological images and CT images. Complex exvivo plaque specimen were evaluated at a high field 9.4T MRI system with different contrasts (T1-fatsat-GRE, T2*-GRE, T2-RARE, PD-RARE) and high resolution (ca. 100m3). Plaque-images were processed to enhance specific plaque-components and combined into RGB-images. The resulting images were interactively explored in coupled views of volume-rendering and user-defined MPRs. CT images were also preprocessed for visualization. The user could then explore corresponding image regions in MR images, histological images and CT images. Initial results showed a benefit for the assessment of plaque-constitution and 3D-morphology.

Original languageEnglish (US)
Title of host publicationINFORMATIK 2009 - Im Focus das Leben, Beitrage der 39. Jahrestagung der Gesellschaft fur Informatik e.V. (GI)
Pages1359-1369
Number of pages11
StatePublished - 2009
Event39th Jahrestagung der Gesellschaft fur Informatik e.V. (GI): Im Focus das Leben, INFORMATIK 2009 39th Annual Meeting of the German Informatics Society (GI): Focus on Life, INFORMATIK 2009 - Lubeck, Germany
Duration: Sep 28 2009Oct 2 2009

Publication series

NameINFORMATIK 2009 - Im Focus das Leben, Beitrage der 39. Jahrestagung der Gesellschaft fur Informatik e.V. (GI)

Other

Other39th Jahrestagung der Gesellschaft fur Informatik e.V. (GI): Im Focus das Leben, INFORMATIK 2009 39th Annual Meeting of the German Informatics Society (GI): Focus on Life, INFORMATIK 2009
CountryGermany
CityLubeck
Period9/28/0910/2/09

ASJC Scopus subject areas

  • Information Systems

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