TY - GEN
T1 - Visual classification of complicated plaques based on multidimensional image fusion
AU - Hennemuth, A.
AU - Harloff, A.
AU - Spehl, T.
AU - Pavlov, N.
AU - Friman, O.
AU - Paul, D.
AU - Elverfeldt, D. V.
AU - Kuehnel, C.
AU - Wirtz, S.
AU - Goebel, H.
AU - Mannheim, J.
AU - Hahn, H. K.
AU - Pichler, B.
AU - Hennig, J.
AU - Markl, M.
PY - 2009
Y1 - 2009
N2 - Multi-contrast MRI has shown to be suitable for plaque analysis, which is important for the risk assessment of internal carotid artery stenoses. The purpose of this work was the development of software prototypes, which support the development of methods for the classification and exploration of plaque-morphology in 3D and allow for a comparison with histological images and CT images. Complex exvivo plaque specimen were evaluated at a high field 9.4T MRI system with different contrasts (T1-fatsat-GRE, T2*-GRE, T2-RARE, PD-RARE) and high resolution (ca. 100m3). Plaque-images were processed to enhance specific plaque-components and combined into RGB-images. The resulting images were interactively explored in coupled views of volume-rendering and user-defined MPRs. CT images were also preprocessed for visualization. The user could then explore corresponding image regions in MR images, histological images and CT images. Initial results showed a benefit for the assessment of plaque-constitution and 3D-morphology.
AB - Multi-contrast MRI has shown to be suitable for plaque analysis, which is important for the risk assessment of internal carotid artery stenoses. The purpose of this work was the development of software prototypes, which support the development of methods for the classification and exploration of plaque-morphology in 3D and allow for a comparison with histological images and CT images. Complex exvivo plaque specimen were evaluated at a high field 9.4T MRI system with different contrasts (T1-fatsat-GRE, T2*-GRE, T2-RARE, PD-RARE) and high resolution (ca. 100m3). Plaque-images were processed to enhance specific plaque-components and combined into RGB-images. The resulting images were interactively explored in coupled views of volume-rendering and user-defined MPRs. CT images were also preprocessed for visualization. The user could then explore corresponding image regions in MR images, histological images and CT images. Initial results showed a benefit for the assessment of plaque-constitution and 3D-morphology.
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M3 - Conference contribution
AN - SCOPUS:84874322735
SN - 9783885792482
T3 - INFORMATIK 2009 - Im Focus das Leben, Beitrage der 39. Jahrestagung der Gesellschaft fur Informatik e.V. (GI)
SP - 1359
EP - 1369
BT - INFORMATIK 2009 - Im Focus das Leben, Beitrage der 39. Jahrestagung der Gesellschaft fur Informatik e.V. (GI)
T2 - 39th Jahrestagung der Gesellschaft fur Informatik e.V. (GI): Im Focus das Leben, INFORMATIK 2009 39th Annual Meeting of the German Informatics Society (GI): Focus on Life, INFORMATIK 2009
Y2 - 28 September 2009 through 2 October 2009
ER -