Visual neglect during intracarotid amobarbital testing

P. A. Spiers; D. L. Schomer; H. W. Blume; J. Kleefield; G. O’Reilly; S. Weintraub; P. Osbome-Shaefer; M. M. Mesulam

doi:10.1212/wnl.40.10.1600

Visual neglect during intracarotid amobarbital testing

P. A. Spiers^*, D. L. Schomer, H. W. Blume, J. Kleefield, G. O’Reilly, S. Weintraub, P. Osbome-Shaefer, M. M. Mesulam

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

The unilateral suppression of hemispheric function by sodium amobarbital may result in hemispatial visual neglect, as measured by performance on a random letter cancellation task. Our study not only investigates this hypothesis but also attempts to identify more precisely the anatomic locus of control for directed attention to extrapersonal space by correlating scanning performance with EEG activity. Forty-eight consecutive patients with epilepsy underwent preoperative intracarotid amobarbital tests. The results indicated that disruption of scanning and contralateral neglect occurred only after right- hemisphere suppression and seemed specifically related to changes in right frontal lobe EEG activity. This pattern of performance held not only for right-handed subjects, but also for those who were left-handed, and even for those who had right- hemisphere language dominance.

Original language	English (US)
Pages (from-to)	1600-1606
Number of pages	7
Journal	Neurology
Volume	40
Issue number	10
DOIs	https://doi.org/10.1212/wnl.40.10.1600
State	Published - Oct 1990

ASJC Scopus subject areas

Clinical Neurology

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10.1212/wnl.40.10.1600

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abstract = "The unilateral suppression of hemispheric function by sodium amobarbital may result in hemispatial visual neglect, as measured by performance on a random letter cancellation task. Our study not only investigates this hypothesis but also attempts to identify more precisely the anatomic locus of control for directed attention to extrapersonal space by correlating scanning performance with EEG activity. Forty-eight consecutive patients with epilepsy underwent preoperative intracarotid amobarbital tests. The results indicated that disruption of scanning and contralateral neglect occurred only after right- hemisphere suppression and seemed specifically related to changes in right frontal lobe EEG activity. This pattern of performance held not only for right-handed subjects, but also for those who were left-handed, and even for those who had right- hemisphere language dominance.",

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AU - Spiers, P. A.

AU - Schomer, D. L.

AU - Blume, H. W.

AU - Kleefield, J.

AU - O’Reilly, G.

AU - Weintraub, S.

AU - Osbome-Shaefer, P.

AU - Mesulam, M. M.

PY - 1990/10

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AB - The unilateral suppression of hemispheric function by sodium amobarbital may result in hemispatial visual neglect, as measured by performance on a random letter cancellation task. Our study not only investigates this hypothesis but also attempts to identify more precisely the anatomic locus of control for directed attention to extrapersonal space by correlating scanning performance with EEG activity. Forty-eight consecutive patients with epilepsy underwent preoperative intracarotid amobarbital tests. The results indicated that disruption of scanning and contralateral neglect occurred only after right- hemisphere suppression and seemed specifically related to changes in right frontal lobe EEG activity. This pattern of performance held not only for right-handed subjects, but also for those who were left-handed, and even for those who had right- hemisphere language dominance.

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Visual neglect during intracarotid amobarbital testing

Abstract

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