Visualization of Multidirectional Regional Left Ventricular Dynamics by High-Temporal-Resolution Tissue Phase Mapping

Daniela Föll, Bernd Jung, Felix Staehle, Elfriede Schilli, Christoph Bode, Jürgen Hennig, Michael Markl*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


Purpose: To apply high-temporal-resolution tissue phase mapping (TPM) to derive a detailed representation of nor- mal regional myocardial motion in a large cohort of 58 normal subjects (three age groups) and one patient with dilated cardiomyopathy. Materials and Methods: Analysis included transformation of the acquired myocardial velocities into radial, circumfer- ential, and long-axis motion components representing left ventricular (LV) function with a spatiotemporal resolution of 1.3 × 2.6 × 8mm3 and 13.8 msec, respectively. To compare multidirectional regional myocardial velocities be- tween groups of subjects, a multisegment and multislice visualization model was employed. Regional myocardial motion was mapped onto the visualization model to display the current status of myocardial motion from base to apex as in-plane velocity vector fields in conjunction with color- coded long-axis plane motion. Moreover, correlation anal- ysis was used to investigate regional differences in myocar- dial dynamics. Results: Age-related changes in LV myocardial velocities resulted in significant differences of peak and time-to-peak velocities in the radial and long-axis directions. Correlation analysis revealed clearly visible regional differences in the temporal evolution of long-axis and circumferential veloci- ties, particularly between the youngest and oldest age groups. Comparison of pathological LV motion with age- matched volunteers indicated marked regional alterations in myocardial velocities and dynamics. Conclusion: High-temporal-resolution TPM in combina- tion with a schematic visualization model and correlation analysis permits the identification of local changes in myo- cardial velocities associated with different age groups and a common LV pathology.

Original languageEnglish (US)
Pages (from-to)1043-1052
Number of pages10
JournalJournal of Magnetic Resonance Imaging
Issue number5
StatePublished - May 2009


  • Cardiac function
  • Heart
  • Myocardial motion
  • Phase contrast
  • Tissue phase mapping

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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