Visualizing cortical activation during mental calculation with functional MRI

Linda Rueckert; Nicholas Lange; Arnaud Partiot; Ildebrando Appollonio; Irene Litvan; Denis Le Bihan; Jordan Grafman

doi:10.1006/nimg.1996.0011

Visualizing cortical activation during mental calculation with functional MRI

Linda Rueckert, Nicholas Lange, Arnaud Partiot, Ildebrando Appollonio, Irene Litvan, Denis Le Bihan, Jordan Grafman^*

^*Corresponding author for this work

Physical Medicine and Rehabilitation

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

Abstract

Cortical activation during arithmetic calculation (silent subtraction by sevens) was compared to that observed during a control condition for which subjects were required to count forward by ones. Nine normal subjects underwent 1.5-T functional magnetic resonance imaging while performing these tasks. All subjects showed bilateral premotor, posterior parietal, and prefrontal cortex activation during serial calculation. There was a large degree of individual variation in activation outside of these areas. These results confirm the role of posterior parietal cortex in arithmetic calculation and implicate parietal cortex in arithmetic calculation and implicate other regions, including prefrontal cortex.

Original language	English (US)
Pages (from-to)	97-103
Number of pages	7
Journal	Neuroimage
Volume	3
Issue number	2
DOIs	https://doi.org/10.1006/nimg.1996.0011
State	Published - Apr 1996

ASJC Scopus subject areas

Neurology
Cognitive Neuroscience

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title = "Visualizing cortical activation during mental calculation with functional MRI",

abstract = "Cortical activation during arithmetic calculation (silent subtraction by sevens) was compared to that observed during a control condition for which subjects were required to count forward by ones. Nine normal subjects underwent 1.5-T functional magnetic resonance imaging while performing these tasks. All subjects showed bilateral premotor, posterior parietal, and prefrontal cortex activation during serial calculation. There was a large degree of individual variation in activation outside of these areas. These results confirm the role of posterior parietal cortex in arithmetic calculation and implicate parietal cortex in arithmetic calculation and implicate other regions, including prefrontal cortex.",

author = "Linda Rueckert and Nicholas Lange and Arnaud Partiot and Ildebrando Appollonio and Irene Litvan and {Le Bihan}, Denis and Jordan Grafman",

note = "Funding Information: Dr. Appollonio was supported by a grant from the Italian National Research Council and by the generous sponsorship of the Lions Club {\textquoteleft}{\textquoteleft}Milan Al Cenacolo Vinciano{\textquoteright}{\textquoteright}—Italy. We thank two anonymous reviewers for their helpful comments on an earlier version of the manuscript.",

year = "1996",

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doi = "10.1006/nimg.1996.0011",

language = "English (US)",

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T1 - Visualizing cortical activation during mental calculation with functional MRI

AU - Rueckert, Linda

AU - Lange, Nicholas

AU - Partiot, Arnaud

AU - Appollonio, Ildebrando

AU - Litvan, Irene

AU - Le Bihan, Denis

AU - Grafman, Jordan

N1 - Funding Information: Dr. Appollonio was supported by a grant from the Italian National Research Council and by the generous sponsorship of the Lions Club ‘‘Milan Al Cenacolo Vinciano’’—Italy. We thank two anonymous reviewers for their helpful comments on an earlier version of the manuscript.

PY - 1996/4

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N2 - Cortical activation during arithmetic calculation (silent subtraction by sevens) was compared to that observed during a control condition for which subjects were required to count forward by ones. Nine normal subjects underwent 1.5-T functional magnetic resonance imaging while performing these tasks. All subjects showed bilateral premotor, posterior parietal, and prefrontal cortex activation during serial calculation. There was a large degree of individual variation in activation outside of these areas. These results confirm the role of posterior parietal cortex in arithmetic calculation and implicate parietal cortex in arithmetic calculation and implicate other regions, including prefrontal cortex.

AB - Cortical activation during arithmetic calculation (silent subtraction by sevens) was compared to that observed during a control condition for which subjects were required to count forward by ones. Nine normal subjects underwent 1.5-T functional magnetic resonance imaging while performing these tasks. All subjects showed bilateral premotor, posterior parietal, and prefrontal cortex activation during serial calculation. There was a large degree of individual variation in activation outside of these areas. These results confirm the role of posterior parietal cortex in arithmetic calculation and implicate parietal cortex in arithmetic calculation and implicate other regions, including prefrontal cortex.

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