Vitamin D deficiency predicts prostate biopsy outcomes

Adam B. Murphy*, Yaw Nyame, Iman K. Martin, William J. Catalona, Courtney M P Hollowell, Robert B. Nadler, James M. Kozlowski, Kent T. Perry, Andre Kajdacsy-Balla, Rick Kittles

*Corresponding author for this work

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Purpose: The association between vitamin D and prostate biopsy outcomes has not been evaluated. We examine serum vitamin D levels with prostate biopsy results in men with an abnormal prostate-specific antigen and/or digital rectal examination. Experimental Design: Serum 25-hydroxyvitamin D (25-OH D) was obtained from 667 men, ages 40 to 79 years, prospectively enrolled from Chicago urology clinics undergoing first prostate biopsy. Logistic regression was used to evaluate the associations between 25-OH D status and incident prostate cancer, Gleason score, and tumor stage. Results: Among European American (EA) men, there was an association of 25-OH D

Original languageEnglish (US)
Pages (from-to)2289-2299
Number of pages11
JournalClinical Cancer Research
Volume20
Issue number9
DOIs
StatePublished - May 1 2014

Fingerprint

Vitamin D Deficiency
Prostate
Biopsy
Vitamin D
Digital Rectal Examination
Neoplasm Grading
Urology
Prostate-Specific Antigen
Serum
Prostatic Neoplasms
Research Design
Logistic Models
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

Cite this

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title = "Vitamin D deficiency predicts prostate biopsy outcomes",
abstract = "Purpose: The association between vitamin D and prostate biopsy outcomes has not been evaluated. We examine serum vitamin D levels with prostate biopsy results in men with an abnormal prostate-specific antigen and/or digital rectal examination. Experimental Design: Serum 25-hydroxyvitamin D (25-OH D) was obtained from 667 men, ages 40 to 79 years, prospectively enrolled from Chicago urology clinics undergoing first prostate biopsy. Logistic regression was used to evaluate the associations between 25-OH D status and incident prostate cancer, Gleason score, and tumor stage. Results: Among European American (EA) men, there was an association of 25-OH D",
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Vitamin D deficiency predicts prostate biopsy outcomes. / Murphy, Adam B.; Nyame, Yaw; Martin, Iman K.; Catalona, William J.; Hollowell, Courtney M P; Nadler, Robert B.; Kozlowski, James M.; Perry, Kent T.; Kajdacsy-Balla, Andre; Kittles, Rick.

In: Clinical Cancer Research, Vol. 20, No. 9, 01.05.2014, p. 2289-2299.

Research output: Contribution to journalArticle

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AU - Murphy, Adam B.

AU - Nyame, Yaw

AU - Martin, Iman K.

AU - Catalona, William J.

AU - Hollowell, Courtney M P

AU - Nadler, Robert B.

AU - Kozlowski, James M.

AU - Perry, Kent T.

AU - Kajdacsy-Balla, Andre

AU - Kittles, Rick

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