Vitamin D deficiency predicts prostate biopsy outcomes

Adam B. Murphy*, Yaw Nyame, Iman K. Martin, William J. Catalona, Courtney M P Hollowell, Robert B. Nadler, James M. Kozlowski, Kent T. Perry, Andre Kajdacsy-Balla, Rick Kittles

*Corresponding author for this work

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Purpose: The association between vitamin D and prostate biopsy outcomes has not been evaluated. We examine serum vitamin D levels with prostate biopsy results in men with an abnormal prostate-specific antigen and/or digital rectal examination. Experimental Design: Serum 25-hydroxyvitamin D (25-OH D) was obtained from 667 men, ages 40 to 79 years, prospectively enrolled from Chicago urology clinics undergoing first prostate biopsy. Logistic regression was used to evaluate the associations between 25-OH D status and incident prostate cancer, Gleason score, and tumor stage. Results: Among European American (EA) men, there was an association of 25-OH D

Original languageEnglish (US)
Pages (from-to)2289-2299
Number of pages11
JournalClinical Cancer Research
Volume20
Issue number9
DOIs
StatePublished - May 1 2014

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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