Abstract
Asthma occurs as complex interactions of the environmental and genetics. Clinical studies and animal models of asthma indicate dietary factors such as vitamin E and vitamin D as protective for asthma risk. In this review, we discuss opposing regulatory functions of tocopherol isoforms of vitamin E and regulatory functions of vitamin D in asthma and how the variation in global prevalence of asthma may be explained, at least in part, by these dietary components.
Original language | English (US) |
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Pages (from-to) | 364-372 |
Number of pages | 9 |
Journal | International Immunopharmacology |
Volume | 23 |
Issue number | 1 |
DOIs | |
State | Published - Nov 2014 |
Funding
Sources of support: This study was supported by the National Institutes of Health Grants R01 AT004837 (J.M.C-M.) and HL98096 (P.C.A.) and Ernest S. Bazley Grant .
Keywords
- Animal models
- Asthma-α-Tocopherol
- Human
- Vitamin D
- γ-Tocopherol
ASJC Scopus subject areas
- Immunology and Allergy
- Pharmacology
- Immunology